- Elsewhere on Sunday, Crystal Palace topped visiting Bournemouth by five goals to three, West Ham clinched a top-10 finish with a 4-1 road win at Watford, Newcastle ended the campaign with an impressive 4-0 win at relegated Fulham, and relegated Huddersfield stole a point at Southampton.
Brighton’s attempts to end the season on a high note after surviving relegation fell short as Manchester City roared back from a goal down in spectacular style to hand them a 4-1 thrashing at the Amex, a result that ended Liverpool’s magnificent challenge for the title.
City Coach, Guardiola is thrown into the air after his side beat Brighton 4-1 to finish one point ahead of title rivals Liverpool.
Leicester and Chelsea played out a low-key end-of-season affair which ended goalless at the King Power Stadium, Tottenham sealed a fourth-place finish in an entertaining but surprising 2-2 tie at home with Everton, Pierre-Emerick Aubameyang scored twice as Arsenal beat Burnley, but the Gunners failed to finish in the top four for the third successive season, relegated Cardiff City heaped more misery on a disappointing Manchester United team that saw the latter go down 2-0 at home.
English Premier League Week 38 Standings
Elsewhere on Sunday, Crystal Palace topped visiting Bournemouth by five goals to three, West Ham clinched a top-10 finish with a 4-1 road win at Watford, Newcastle ended the campaign with an impressive 4-0 win at relegated Fulham, and relegated Huddersfield stole a point at Southampton.
Brighton 1-4 Manchester City
Manchester City came from behind to retain the Premier League title in style with a 4-1 victory at Brighton on the final day of the season.
City looked on course for a nerve-jangling final outing at the Amex Stadium when Sadio Mane's opener for Liverpool against Wolves - which temporarily moved the Reds top of the table - was compounded by Glenn Murray heading Brighton into the lead on 27 minutes.
But City produced the response of champions. Sergio Aguero struck just 83 seconds after Murray's opener, before Aymeric Laporte's header secured a half-time lead.
Riyad Mahrez rifled City's third into the top corner on 63 minutes before an exquisite Ilkay Gundogan free-kick sparked wild scenes of celebrations among Pep Guardiola's players and staff.
City's 14th consecutive league victory sees them end one of the most remarkable Premier League title races on top of the pile with 98 points and sees them become the first side since 2009 to retain the title.
Burnley 1-3 Arsenal
Arsenal finished their campaign on a high in a frantic 3-1 win over Burnley at Turf Moor on Sunday, as Pierre-Emerick Aubameyang secured a share in the Golden Boot with a brace.
Burnley had the better chances of a frenetic first half that saw Chris Wood hit the post before Matt Lowton's shot was cleared off the line.
But Aubameyang (52) capitalised on some shaky defending to break the deadlock, before doubling Arsenal's lead (63) with a volley.
Ashley Barnes (65) pulled one back almost immediately, but substitute Eddie Nketiah (90+4) secured all three points in stoppage time as the Gunners finished fifth in the table.
Crystal Palace 5-3 Bournemouth
Crystal Palace hit five goals past Bournemouth in a dramatic 5-3 victory in their final game of the season.
Palace and Bournemouth entertained the fans in an enthralling encounter which was kick-started by Michy Batshuayi, who scored two in quick succession (24 & 32).
Jack Simpson scored an unfortunate own goal five minutes later before Jefferson Lerma smashed in a screamer on the stroke of half-time (45).
Patrick van Aanholt slotted home Palace's fourth in the 65th minute, before Bournemouth grabbed another two thanks to strikes from Jordon Ibe (56) and Josh King (73).
But Andros Townsend ensured Palace would finish the season victorious with a neat finish 10 minutes from time.
Fulham 0-4 Newcastle
Fulham bowed out with a 4-0 defeat to Newcastle at Craven Cottage on the final day.
The hosts suffered a double blow inside 11 minutes as Jonjo Shelvey volleyed a superb effort (9) before Ayoze Perez continued his fine scoring form just two minutes later.
Fulham were seeing plenty of possession when Fabian Schar had a free header in the 61st minute for Newcastle's third and, although Scott Parker's side had the ball in the back of the net soon afterwards, it was incorrectly ruled out for offside.
Salomon Rondon rounded off the victory in the 89th minute as the Magpies ended the season in 13th place. Fulham ended in 19th place but have long known they will play in the Sky Bet Championship next season.
Leicester 0-0 Chelsea
Poor finishing cost Leicester and Chelsea a win, as the two sides played out a 0-0 draw in the final game of the season.
Ross Barkley should have opened the scoring early on for Chelsea when Jorginho chipped the ball over the Leicester defence for his fellow midfielder to run on to, but his fierce shot was blocked by Kasper Schmeichel's chest.
Cesar Azpilicueta slipped not once, but twice, to allow Jamie Vardy a run through on goal but when the crunch moment came he sent a poor pass to Youri Tielemans, who could not fashion a meaningful chance from a poor angle, allowing Willy Caballero the chance to save.
There were fond farewells for Leicester as Shinji Okazaki and Danny Simpson were brought on for their final appearances, much to the appreciation of the home supporters.
For Chelsea, Eden Hazard eventually came on in the second half, potentially for the last time as rumours about his future continue.
Liverpool 2-0 Wolves
Sadio Mane scored a double but Liverpool's 2-0 victory over Wolves was in vain as they fell just a point short of Manchester City after a pulsating Premier League title race.
City's 4-1 win at Brighton means they retain the title ahead of Liverpool, whose 29-year wait for a top-flight title goes on despite a record tally of 97 points for a second-place side.
Needing a win and for City to drop points at Brighton, Liverpool took the lead through Mane's close-range finish (17), before Mane headed home a second late on (81) to wrap up a victory, and the home fans gave Liverpool a huge ovation at full time as attention now turns to the Champions League final against Tottenham on June 1. Wolves finish seventh.
Manchester United 0-2 Cardiff
Nathaniel Mendez-Laing's double ended Manchester United's wretched season on a sour note with a 2-0 home defeat by relegated Cardiff.
Arsenal's win over Burnley guaranteed United would be unable to finish fifth regardless of the scoreline at Old Trafford, but they put in a grimly familiar performance devoid of the intensity, passion or quality required, albeit also lacking luck against a Cardiff side handed a slice of fortune from referee John Moss in opening the scoring.
Cardiff winger Mendez-Laing received the slightest of touches from Diogo Dalot's sliding challenge to go down in the area, before picking himself up to beat David De Gea from the spot (23).
Striker Mason Greenwood, United's youngest starter in Premier League history, had a number of chances and was inches from scoring when Neil Etheridge turned his close-range effort onto the post, but his bright performance was one of few plus points from a miserable afternoon at Old Trafford.
They had other chances to level but could not honestly say they were better than 18th-placed Cardiff, the first relegated side to beat a top-six team this season.
And the visitors' second summed up United's season, with some calamitous defending allowing Mendez-Laing to slot in unmarked after half time and double an advantage Cardiff would hold comfortably.
Southampton 1-1 Huddersfield
Nathan Redmond's wonder-goal was not enough for Southampton as they were held to a 1-1 draw by Huddersfield.
Redmond put Southampton into the lead (41) with an outstanding curling shot into the top corner after a solo run from the left flank.
Debutant goalkeeper Joel Coleman kept Huddersfield on level terms with an outstanding fingertip save to keep out James Ward-Prowse's shot with the help of the crossbar.
Charlie Austin went close in stoppage time but the Terriers held on to survive a late onslaught from the hosts and bow out of the Premier League with a hard-fought point.
Tottenham 2-2 Everton
Tottenham confirmed their place in the Champions League for a fourth successive season after playing out an entertaining 2-2 draw with Everton.
Eric Dier slammed the hosts in front after three minutes, but Everton responded with two quick-fire goals through Theo Walcott (69) and Cenk Tosun (72) in the second period.
Christian Eriksen's low free-kick ensured a share of the spoils as Mauricio Pochettino's side marked their homecoming following their midweek Champions League exploits by earning only a second league draw of the season.
Spurs will now turn their focus on overcoming Liverpool in the Madrid final on June 1, having finished in fourth place, while the point ensures Everton finish the season once more in eighth position.
Watford 1-4 West Ham
Mark Noble scored twice as West Ham thrashed 10-man Watford 4-1 at Vicarage Road to leapfrog their hosts and secure a top-half finish.
West Ham were two up against the run of play at the break, after captain Noble capped a fine individual effort by slotting home from the edge of the box on 15 minutes and Manuel Lanzini (38) reacted quickest to nod home after Ben Foster had tipped Michail Antonio's drive onto the bar.
But while the impressive Gerard Deulofeu (46) pounced on a Pablo Zabaleta error immediately after the restart to give Watford hope, Jose Holebas' straight red for tripping Antonio handed the advantage to West Ham - and also means he misses Saturday's FA Cup final with Manchester City.
EPL Week 38 Scores At A Glance
Brighton 1-4 Manchester City
Burnley 1-3 Arsenal
Crystal Palace 5-3 Bournemouth
Fulham 0-4 Huddersfield
Leicester 0-0 Chelsea
Liverpool 2-0 Wolves
Manchester United 0-2 Cardiff
Southampton 1-1 Huddersfield
Tottenham 2-2 Everton
Watford 1-4 West Ham
Match day reports from BBC and skysports were used in this compilation.
